I found this article at MedGadget blog today about a researcher at the Hebrew University of Jerusalem that found a way to control bacterial activity without antibiotics, he interferes with their communication process. Only recently has it been discovered that the bacteria assembled in biofilms have a network of communication between them called “quorum sensing,”…
Primary Immunodeficiency
The IDF recommends to declare a public health emergency
“We cannot allow patients to die,” said Marcia Boyle, CEO and chair of the Immune Deficiency Foundation (IDF). “We have an FDA-approved lifesaving therapy that cannot be used in physicians’ offices because the MMA reduced reimbursement to the point that the medication isn’t affordable. We are counting on Sec. Leavitt to provide immediate relief to…
Blood Works @ Forbes.com
If I understand correctly they are trying to educate the immune system to prevent inflammation. What side effects does this have? Blood Works by Mary Ellen Egan, A novel therapy using patients’ own blood may reverse a deadly component of heart disease. The human body is constantly bombarded with foreign microorganisms and antigens, a battle…
The book
I’m writing a book! Paulina remembers more things than I do, she has a better memory(among lots of other things). I constantly go to Paulina with questions looking for more details so when I say ‘I” it really means ‘We’. I (we) started to write formally around February 23rd. 2005 after Andy’s last hospitalization. I…
Gene Therapy Is Facing a Crucial Hearing @ The New York Times
More about gene therapy.. Interesting data: By GARDINER HARRIS; Published: March 3, 2005 The French study was once hailed as one of the first breakthroughs in gene therapy: 10 children suffering from a rare immune disorder were largely cured. But three of those children have since developed leukemia, and one of the three has died….
FDA Halts Gene Therapy Experiments @ The Washington Post
I contacted Dr. Alain Fischer once, read message here. And his response here. FDA Halts Gene Therapy Experiments; By Rick Weiss, Washington Post Staff Writer, Thursday, March 3, 2005; 2:20 PM The Food and Drug Administration has suspended several U.S. gene therapy experiments after learning that a third child who underwent treatment in France has…
Dr. Jordan Orange – NBC News
A story from NBC News uses Dr. Orange’s words: “A person with primary immune deficiency is unable to protect themselves from even common infections,” said Dr. Jordan Orange, a pediatric immunologist. “What we’re doing with this treatment is replacing that missing part of her immune system,” Orange said. Dr. Jordan Orange found NEMO, Andy’s primary…
Dr. Ashish Jain publishes article about NEMO with Dr. Jordan Orange
Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation. Jain, A., Ma, C. A., Lopez-Granados, E., Means, G., Brady, W., Orange, J. S., Liu, S., Holland, S., Derry, J. M.J. J. Clin. Invest. 2004 114: p. 1593-1602 Read the article here.
Dr. Jordan Orange publishes article about NEMO PI without ectodermal dysplasia.
On the Journal of Clinical Allergy and Immunology: Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia.
Bacteria killing article @ The Journal of Clinical Infectious Diseases
Bacteria-Killing vs. Bacteria-Inhibiting Drugs in Treating Infections When treating an infection, physicians may face a choice between using a bactericidal (bacteria-killing) drug, a bacteriostatic (bacteria-inhibiting) drug or a combination of the two. The solution is not always obvious, particularly since a drug that is bactericidal for one strain of bacteria may only inhibit the growth…